Vanderbilt researchers guide muscle cells into spiral shapes for tiny blood vessels
A team at Vanderbilt University has demonstrated how smooth muscle cells can self-organize into spirals to help engineer microvessels that regulate blood flow.
New method creates active microvessels
Researchers have long struggled to recreate resistance vessels with the specific structure and function of natural counterparts. Previous work produced channels for fluids but could not make them actively change their diameter. This new study addresses that gap by showing how cells organize themselves into the required architecture.
Study published in journal
Leon Bellan, an associate professor of mechanical engineering and biomedical engineering, led the project with his team. The findings were published in the journal Advanced Healthcare Materials. These results advance efforts to build vessels that meet changing demands in different tissues.
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