Researchers identify first bacterial galactose oxidase enzyme for greener production
Scientists at Instituto de Tecnologia Química e Biológica António Xavier in Lisbon have described the first galactose oxidase found in bacteria.
AI helps solve production challenges
The enzyme proved difficult to produce in a soluble form for several years. AlphaFold, an artificial intelligence system, provided structural predictions that helped researchers understand the enzyme's unusual architecture. These predictions allowed the team to identify changes that could improve its production.
Study published in chemical journal
The research team published their findings in the journal Chem & Bio Engineering. Their bacterial counterparts differ from the best-characterized fungal galactose oxidases currently available. This discovery expands the toolkit for producing pharmaceuticals and food ingredients under mild conditions.
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