Researchers study 194-year-old tortoise to understand its slow aging process
Scientists examined the genome of Jonathan, a 194-year-old Aldabra giant tortoise, to identify genetic factors contributing to his extreme longevity.
Unique gene variants found in old tortoise
The research team identified 287 specific gene variants that reduce typical aging effects. These genetic changes help repair DNA damage and regulate insulin levels within the body.
Epigenome switches remain stable over time
Comparisons showed that the on-off switches controlling metabolism genes in Jonathan are similar to those in younger relatives. Usually, these switches change as an animal ages, but they stayed consistent in this individual.
Study marks first epigenome investigation
This project represents the initial analysis of a giant tortoise epigenome published in Science Advances. The findings suggest that a lack of genetic wear and tear keeps the animal alive for nearly two centuries.
2 outlets, different leads
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Phys.org
194-year-old tortoise reveals stable gene switches that may help resist aging
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NPR
Study finds 194-year-old tortoise is 'aging more slowly than you would expect'
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2 independent outlets. Headlines as published. Links open the original report.