Researchers combine amino acid with colistin to treat resistant infections
Chinese scientists report that adding the amino acid L-arginine restores sensitivity in bacteria resistant to the last-resort antibiotic colistin.
New method reverses drug resistance
Researchers in China found that mixing colistin with L-arginine changes the bacterial cell membrane. This structural change allows the antibiotic to enter the cell and trigger the production of reactive oxygen species. The resulting chemical reaction kills the bacterium effectively.
Animal trials show success
Experiments conducted on mice demonstrated that the combination treated infections caused by colistin-resistant pathogens. These findings suggest a rational strategy to overcome rising rates of resistance in gram-negative bacteria. The approach addresses a critical need as resistant infections rise worldwide.
Reported by one outlet
Only one outlet has published this. Nothing here has been checked against a second report, so read it as that outlet's account and follow the link below for the original.
Reported by
1 independent outlet. Headline as published. Links open the original report.