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UVA scientists develop sound wave method to treat brain cancer

Researchers at the University of Virginia Health System announced a new experimental strategy for treating glioblastoma on November 1, 2026.

Scientists use sound waves to deliver a new attack on deadly brain cancer
File photo Scientists use sound waves to deliver a new attack on deadly brain cancer Photo: ScienceDaily

Combining ultrasound with genetic molecules

The team combined focused ultrasound, tiny nanoparticles, and microscopic bubbles to deliver microRNAs into the brain. These microRNAs are designed to interfere with several genes responsible for tumor growth. This combination allows the treatment to cross the brain's protective barrier temporarily.

Targeting multiple cancer-driving genes

Roger Abounader led the research effort at the University of Virginia Comprehensive Cancer Center. The new approach aims to attack multiple cancer-driving genes simultaneously rather than targeting a single pathway. This strategy could help overcome obstacles that have limited existing brain cancer treatments.

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