Study suggests Zepbound and Mounjaro activate brown fat in mice
Researchers at the University of Barcelona reported on September 26, 2026, that tirzepatide may activate calorie-burning brown fat in obese mice.
Drug activates specific tissue type
Scientists found that tirzepatide, sold as Mounjaro or Zepbound, activated brown adipose tissue in laboratory animals. This form of fat specializes in using energy to burn calories. The study indicates the drug works beyond simply suppressing appetite.
Team led by Marion Peyrou
Marion Peyrou from the University of Barcelona and the Sant Joan de Déu Research Institute directed the project. Her team worked with the CIBER in Physiopathology of Obesity and Nutrition to analyze the metabolic effects. The findings offer new clues about how the medication functions inside the body.
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