Study reveals Maria Branyas showed signs of extreme aging and youth at 117
Researchers at the Josep Carreras Leukaemia Research Institute published final results on September 11, 2026, describing how 117-year-old Maria Branyas displayed both advanced aging markers and biological protection.

Biological age younger than years lived
The team found that her biological age was lower than her chronological age despite living past 117. She exhibited low levels of inflammation and maintained beneficial gut bacteria throughout her life. These protective genetic features allowed her to avoid major diseases common in older populations.
Aging process distinct from disease prevention
Because she avoided illness, the study provided a rare view of aging itself rather than typical age-related conditions. Scientists noted that extreme longevity involves intense aging occurring alongside powerful biological protection mechanisms. This finding suggests future treatments might address aging changes similarly to how they treat specific diseases.
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