Scientists map mitochondrial proteins across six diverse organisms in new study
Researchers published findings on mitochondrial proteins from five parasites and one plant in nine papers released between October 1 and 9.
New protein catalogues reveal shared traits
The project analyzed the proteins that make up mitochondria in six specific organisms. Scientists identified dozens of proteins found in parasites but absent in humans. These shared proteins include some linked to diseases like malaria and sleeping sickness.
Findings spark debate on origins
The results have renewed discussion regarding how the mitochondrion originally formed within eukaryotic cells. Most current knowledge about these organelles comes from studies of humans and yeast. This new work expands understanding beyond those traditional models.
Potential for new treatments
Understanding these unique proteins could help scientists devise new therapies for parasitic illnesses. The research team led by Vamsi Mootha at Howard Hughes Medical Institute in Boston. Their work appears in journals including Cell and Molecular Cell.
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