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Researchers at Chalmers University develop AI scientist for yeast research

Scientists at Chalmers University of Technology in Sweden have created an AI system that autonomously generates and validates new biological discoveries on brewer's yeast.

AI scientist autonomously generates and validates new biological discoveries
File photo AI scientist autonomously generates and validates new biological discoveries Photo: Phys.org

System combines reasoning with automation

The team merged large language models, automated reasoning, and laboratory automation to build a closed-loop lab. This setup allows the artificial intelligence to identify promising questions without needing constant human oversight. The system feeds on existing data including the organism's genome and previous metabolic studies.

AI evaluates outcomes iteratively

The program recommends specific experiments to test its hypotheses before evaluating the results. It then uses new evidence to refine its own understanding of the biological processes. Researchers say this approach moves beyond simple decision support tools to actively creating knowledge.

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