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Northeastern University researchers find deep sexual differences in C. elegans brain activity

A team at Northeastern University examined the nervous systems of male and hermaphrodite C. elegans worms to compare their brain structures and responses to stimuli.

What a worm's brain can teach us about sex differences in the nervous system
File photo What a worm's brain can teach us about sex differences in the nervous system Photo: Phys.org

Neuron counts differ by sex

Hermaphrodite worms possess exactly 302 neurons distributed throughout their nervous system. In contrast, male worms have roughly 387 neurons located in similar areas. About 200 of the hermaphrodite neurons are found in the head region.

Scientists tested responses to cues

Researchers placed the animals in a controlled environment to observe their reactions. They deployed various stimuli including odors from food and chemical danger signals. The study focused on how male and hermaphrodite brains processed these inputs side by side.

Activity patterns show variation

The team discovered that sexual differences in brain activity run surprisingly deep. These findings highlight distinct ways the two sexes handle information processing. The research provides new data on how nervous systems vary within a single species.

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