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New study finds Ozempic improves physical health but shows little impact on life outcomes

University of Chicago researchers published a National Bureau of Economic Research working paper on September 17, 2026, examining the broader effects of GLP-1 medications.

Ozempic can change your body. Can it change your life?
File photo Ozempic can change your body. Can it change your life? Photo: ScienceDaily

Physical health benefits remain strong

GLP-1 drugs like Ozempic help patients manage blood sugar levels and lower cardiovascular risk. Many users also lose a substantial amount of weight while taking these treatments.

Mental health shows no change

The study found little evidence that using these medications produced measurable changes in mental health or self-rated health. Researchers examined adults with diabetes to see if physical improvements extended into other parts of life.

Social and work status stable

Data indicated no significant shifts in employment rates, marital status, or overall well-being among the participants. The findings suggest that broader life effects may be subtler than the dramatic physical health benefits observed.

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