New study finds Ozempic improves physical health but shows little impact on life outcomes
University of Chicago researchers published a National Bureau of Economic Research working paper on September 17, 2026, examining the broader effects of GLP-1 medications.

Physical health benefits remain strong
GLP-1 drugs like Ozempic help patients manage blood sugar levels and lower cardiovascular risk. Many users also lose a substantial amount of weight while taking these treatments.
Mental health shows no change
The study found little evidence that using these medications produced measurable changes in mental health or self-rated health. Researchers examined adults with diabetes to see if physical improvements extended into other parts of life.
Social and work status stable
Data indicated no significant shifts in employment rates, marital status, or overall well-being among the participants. The findings suggest that broader life effects may be subtler than the dramatic physical health benefits observed.
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