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Injectable nanoparticles restore light response in blind retinas during preclinical study

An international research team published findings in Nature Biomedical Engineering that injectable nanoparticles can make blind retinas respond to light in a preclinical study.

Injectable nanoparticles make blind retinas respond to light in preclinical study
File photo Injectable nanoparticles make blind retinas respond to light in preclinical study Photo: Phys.org

Tiny particles act as light receptors

Researchers injected microscopic particles into the eyes of blind mice. These particles settled near nerve cells and triggered electrical processes when exposed to light. The technology successfully activated nerve cells in retinal tissue from pigs as well.

Signals reach the brain cortex

Experiments detected light-induced signals within the visual cortex of the mouse brains. Researchers observed behavioral responses from the animals after the particles received light exposure. The project began at Aarhus University seven years ago with a goal to create a wireless interface between light and living cells.

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