Cornell scientists find mobile human gene in poxvirus
Scientists at Cornell University published a study in Science reporting the discovery of BC200, a human gene found within a poxvirus that retains mobility while serving brain function.
Gene combines unique traits
The gene called BC200 is primarily expressed in neurons. It originated millions of years ago from a transposon known as a jumping gene. This element can move and insert itself into genomes, a capability never before seen in a functional human gene.
Study challenges previous beliefs
Researchers state that genes repurposed for cellular functions are typically no longer transposable. Cedric Feschotte noted that BC200 was created from a mobile element but has retained its ability to jump. The study confirms this gene serves a clear cellular function despite its mobility.
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