Chemists create AI tool to design life-enhancing enzymes from human ideas
A team led by assistant professor Zhongyue Yang developed an artificial intelligence system called MutexaGPT that helps scientists design custom enzymes, a study published in Nature Computational Science.

Tool translates human intuition into enzyme plans
The new AI tool accepts plain-English requests and uses large language model agents to gather missing information. It builds physics-based models before converting the results into actionable design proposals for scientists. Assistant professor Zhongyue Yang stated that the system elevates scientific work rather than replacing human researchers.
Enzymes support daily life and recycling efforts
Engineered enzymes created with this method can synthesize new medications and preserve nutrient-rich foods. They also help recycle polymers to reduce plastic waste in the environment. The research team aims to address concerns about artificial intelligence taking jobs away from humans.
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