Australian researchers tweak one atom to boost plastic-eating enzymes
Researchers at The Australian National University published new findings in Angewandte Chemie International Edition regarding a single-atom change that improves plastic-degrading enzymes.
Single atom changes improve efficiency
The team introduced precise, single-atom modifications to highly engineered PET hydrolases. This approach allows the enzymes to break down polyethylene terephthalate more effectively without losing stability. Previously, increasing enzyme activity often reduced their structural stability.
Method overcomes engineering limits
Lead author Dr Elwy Abdelkader noted that this technique bypasses the usual trade-off between performance and durability. The study focuses on PETases which are already optimized through computational design and protein engineering. Making such a small change preserves the overall structure of the enzyme.
Potential for waste reduction
These improved enzymes could help solve challenges in recycling one of the world's most common plastics. The research suggests that further optimization is possible beyond current engineering boundaries. This development offers a new path for creating more powerful plastic-eating tools.
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