Researchers evolve enzymes to lower tuberculosis antibiotic production costs
A team led by postdoctoral scholar Ziqi Li published findings on September 23 in Nature about using evolved enzymes to make tuberculosis antibiotic ingredients more efficiently.
New method targets drug costs
The researchers developed a technique to create a specific organic compound needed for new antibiotics. This approach aims to reduce manufacturing expenses for treatments required in low- and middle-income nations. Current production methods often result in significant waste that this new process seeks to eliminate.
Enzymes improve sustainable synthesis
Frances Arnold's group uses nature-based catalytic machinery to build valuable molecules in a desired form. The study describes how these enzymes help produce pharmaceutical applications without the high costs of traditional routes. Li notes that finding an accessible route is essential for reaching patients who need effective drugs most.
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