Researchers describe life with asymptomatic Alzheimer’s disease
A scientist at the Penn Memory Center explains the unique experience of people living with cognitively unimpaired Alzheimer's disease pathology.
Patients feel different after diagnosis
People who learn their amyloid PET scan shows elevated amyloid report feeling distinct from before. These individuals have neither dementia nor mild cognitive impairment but possess evidence of the disease. They describe a change in how they interpret memory lapses and ponder future options. One woman stated that this condition involves her brain rather than acting like a colonoscopy.
Desktop medicine defines new risks
This research focuses on desktop diseases defined by numbers instead of current signs or symptoms. Hypertension and diabetes serve as examples where treatments reduce future risk without relieving present disability. Clinicians now work with clinical trialists and actuaries to discover these conditions through controlled trials. The study aims to validate this new stage and potentially discover a treatment for it.
Study results pending validation
The author is waiting on colleague studies that could validate this pre-clinical stage of the illness. These upcoming results might also lead to discovering an effective treatment for the condition. The first essay sets the stage for a second piece on living at biomarker-defined risk.
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