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Penn State team creates new rapid syphilis test using layered nanoparticles

Researchers at Penn State have developed a new one-step rapid syphilis test that uses layered nanoparticles to detect infection earlier than current methods.

One-step rapid syphilis test uses layered nanoparticles to detect infection earlier
File photo One-step rapid syphilis test uses layered nanoparticles to detect infection earlier Photo: Phys.org

New nanoparticle design improves detection

The team replaced the typical gold nanoparticle with one layered in silver and sealed in more gold. This new configuration produces test lines that are 19% to 46% stronger than those found on comparable devices. The device reliably detects lower concentrations of antibodies that the body makes to fight the syphilis bacteria.

Earlier intervention reduces patient visits

Detecting these low levels allows for earlier interventions and potentially fewer appointments for patients. Symptoms of the infection can mimic many other diseases and come and go without treatment while harm continues. If undetected, the infection can spread to partners and to babies during pregnancy.

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