Newer blood thinners slow cognitive decline in Alzheimer’s patients with atrial fibrillation
Researchers at Karolinska Institutet report that newer NOAC blood thinners may slow cognitive decline in Alzheimer's patients who also have atrial fibrillation, according to a study published in the European Heart Journal on September 18, 2026.
Study findings on drug performance
Patients taking NOACs showed a slower decline in cognitive function compared to those using warfarin or no blood thinners. The researchers noted that this effect was modest each year but could accumulate over time. Earlier research suggested anticoagulants might lower dementia risk, but this study focuses on decline after diagnosis.
Mechanisms behind the improvement
Maria Eriksdotter from Karolinska Institutet suggests the treatment could help cognition by improving blood flow. She also noted that reducing small-scale damage in the brain might contribute to these results. Doctors currently prescribe these drugs to reduce clot and stroke risk in older adults.
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