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New study finds GLP-1 drugs lower diabetes and heart risks better than metformin

Researchers at Mayo Clinic in Scottsdale, Arizona, report that GLP-1 medications reduce blood sugar levels and cardiovascular events more effectively than the standard drug metformin for people with prediabetes.

GLP-1s May Help Lower Diabetes, Heart Risks Better Than Standard Prevention
File photo GLP-1s May Help Lower Diabetes, Heart Risks Better Than Standard Prevention Photo: Healthline

GLP-1 drugs show superior prevention results

A new analysis indicates these treatments are more effective at treating prediabetes than the commonly prescribed medication metformin. The medications helped lower blood sugar to healthy levels in patients who have obesity and prediabetes. Users also faced a reduced chance of progressing from prediabetes to type 2 diabetes compared with those taking metformin.

Cardiovascular benefits appear significant for users

People prescribed these drugs experienced fewer heart attacks, strokes, and heart failure events than the control group. The study authors noted a lower risk of death from any cause among GLP-1 users. These findings suggest an additional option exists for treating people with prediabetes alongside standard care.

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