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New atlas reveals biological differences in young and old colorectal cancer patients

Kimmie Ng of the Dana-Farber Cancer Institute published a new study in Nature Medicine on Thursday detailing a single cell atlas of colorectal tumors.

STAT+: New atlas of colorectal tumors sheds light on why cancers in young people are more dangerous
File photo STAT+: New atlas of colorectal tumors sheds light on why cancers in young people are more dangerous Photo: STAT

Study database covers wide age range

The research team analyzed 189 tumors from patients ranging from their 20s to their 90s. This collection represents the largest biological database of colorectal cancer tumors ever assembled for such comparisons.

Younger patients face worse outcomes

Patients under age 35 often have survival rates that are not as good as those in their 40s or 60s. These younger individuals receive more aggressive treatment yet still struggle with tumors that show more aggressive features.

Atlas helps control past variables

The new technology allows researchers to manage variables that previously confounded earlier studies. Scientists have long believed these cancers must be biologically distinct because younger patients are far more difficult to treat.

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