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KIMS researchers develop plasmonic coating for rapid sepsis diagnosis

A team from the Korea Institute of Materials Science has created a new plasmonic coating technology that detects low levels of bacteria within one hour.

Plasmonic coating on bacterial surfaces paves the way for rapid sepsis diagnosis
File photo Plasmonic coating on bacterial surfaces paves the way for rapid sepsis diagnosis Photo: Phys.org

New detection method avoids culture steps

The research group led by Minyoung Lee and Sunggyu Park grew metal nanostructures directly on bacterial cells. This approach allows trace amounts of viable bacteria to be identified without traditional amplification methods. The process completes in one hour according to the study published in Small Methods.

Antibiotic response assessment takes two hours

The technology can also evaluate how bacteria respond to specific antibiotic treatments within a two-hour window. This capability supports more precise selection of drug regimens for severe infections. Sepsis diagnosis benefits from this rapid identification of the causative pathogen.

Early infection detection remains difficult

Bacterial concentrations in the bloodstream are extremely low during the early stages of an infection. Conventional blood culture testing struggles to find bacteria when numbers are this small. The new method addresses these limitations by detecting trace levels directly.

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