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Immunologists reflect on fifty years since interleukin-2 discovery and its lasting impact

Rafi Ahmed and Steven Rosenberg published a perspective marking the fiftieth anniversary of the interleukin-2 discovery in September.

Opinion: 50 years ago, my colleagues and I pursued basic research science that became revolutionary
File photo Opinion: 50 years ago, my colleagues and I pursued basic research science that became revolutionary Photo: STAT

Discovery timeline and legacy debate

Colleagues published a paper describing interleukin-2 fifty years ago. Some experts say this protein enabled the growth of human T cells for cancer treatment. Others believe it allowed researchers to find the first human retroviruses.

Scientific process and unexpected results

Basic science often leads to outcomes that researchers cannot predict at the start. Supporters of funding note that many major medical advances began with such work. Critics sometimes expect immediate results from scientific projects instead of long-term benefits.

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