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China reduces human epilepsy seizures by 92.6 percent in first trial

Chinese researchers report a 92.6 percent drop in seizures during the first human chemogenetic trial for epilepsy.

A kill switch for epilepsy? China cuts seizures by 92.6% in first human chemogenetic trial
File photo A kill switch for epilepsy? China cuts seizures by 92.6% in first human chemogenetic trial Photo: South China Morning Post

Trial results show major reduction

The study involved patients with refractory epilepsy who did not respond to standard medications. Participants experienced a significant decrease in seizure frequency after receiving the new treatment. Some individuals saw their attacks completely eliminated during the observation period.

New method avoids brain surgery

Traditional operations for this condition often carry risks of permanent neurological damage. The chemogenetic approach offers an alternative that does not require invasive craniotomy procedures. This technique targets abnormal neural discharges without causing irreversible deficits.

Patients face fewer dangerous attacks

Unpredictable seizures can cause convulsions and loss of consciousness for affected people. The new intervention aims to stop these events before they sweep through brain circuits. Results indicate the method works for a third of patients worldwide who are unresponsive.

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