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Addiction clinics report rising kratom and 7-OH withdrawal cases

Addiction clinics across the United States are recording a sharp increase in patients withdrawing from gas station kratom products containing 7-hydroxymitragynine.

Addiction clinics see rising cases of kratom and 7-OH withdrawal
File photo Addiction clinics see rising cases of kratom and 7-OH withdrawal Photo: STAT

Patient numbers surge at clinics

Boulder Care telehealth clinic saw new patient cases involving these substances rise from 3 percent in September 2025 to 14 percent by August 2026. Medical staff describe this rapid increase as quite an explosion within their patient intake figures.

Potent derivatives drive the trend

Most affected patients use newer products with highly concentrated levels of 7-hydroxymitragynine rather than traditional leaf powder. This compound acts directly on brain opioid receptors to create stronger effects than standard kratom alkaloids.

Regulatory agencies flag the risk

The Food and Drug Administration recently identified 7-OH products as an emerging opioid threat for public health. The Drug Enforcement Administration has proposed a ban on these derivatives above a specific concentration threshold.

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